May Reilly

May Reilly Parker, also known to most as Aunt May, is the aunt of Peter Parker and his legal guardian.

The Boy Who Was Bitten
She welcomed her cousin Peter Parker back home when he returned from a fieldtrip to Osborn Laboratories, which pisses her husband off. Aunt May was a little less concerned with that, even though later Ben and May reveal that Osborn Laboratories was responsible for the deaths of the parents of Peter.